Hole Board Device according to the Boissier-Simon method

Additional Info

FEATURE	BENEFIT
Simple and classical test	Reliable, requires very little training
16 holes, each containing 1 pair of IR photocells	Head Plungings are accurately counted
Can be connected to Multifunction Printer	Up to 6 hole boards can be run simultaneously
Can work in conjunction with Videotracking System	Special model for Videotracking available

 

General
Starting	via RESET switch located on the front panel
Activity Counter	4-digit LED display
Self-diagnosis	by test-key and 2-LED configuration
Power Requirement	115 or 230 V, 50/60 Hz, 15 W max.
Operating Temperature	18° to 40° C
Connection to PC	through DELTA 15-pin connector, via Multifunction Printer
Sound Level	negligible
Physical
Dimensions (Board)	40(w)x40(d)x7-18(h)cm
Dimensions (Controller)	15(w)26(d)x25(h)cm
Weight	5.5Kg
Shipping Weight	1.5cm
Packing Dimensions	67x42x53cm
Warranty	6650 is covered by a 24-month warranty

 

 

 

 

D

The exploratory behavior of laboratory rodents is of interest in a number of areas of behavioral pharmacology. The normal mouse of either gender, when confronted with a new environment, will explore holes in the substrate of its environment by poking its nose in and out of the hole a few times, then moving on to the next hole.

Many unconditioned tests, such as the open field, potentially confound general locomotor activity with exploration. The hole-board apparatus appears to avoid this inconvenience, as head-dipping into holes in the floor represents a valid measure of the subject's attraction towards novelty.

The initial exploration activity of the animal and its variations brought about by psychotropic drugs are unmistakably assessed. The nose poke frequency provides an indicator of exploratory behavior.

 

6650	HOLE BOARD, standard package
6651	Control Unit
6652	Board
6653	Dust Cover for the Board
6654	Dust Cover for the Control Unit
6655	Instruction Manual
OPTIONAL
46653	Hole-Board for Videotracking, model for mouse
46652	Hole-Board for Videotracking, model for rat

Bibliography on 6650

• Involvement of the dopaminergic system in the antidepressant-like effect of the lectin isolated from the red marine alga Solieria filiformis in mice TM Abreu, VS Monteiro, ABS Martins, FB Teles… - International Journal of …, 2017
• The anxiolytic-like effect of 6-styryl-2-pyrone in mice involves GABAergic mechanism of action EMC Chaves, JER Honório-Júnior, CNS Sousa… - Metabolic Brain Disease, 2017
• J.C. Castillo-Hernández et alia: "Effect of N-Benzylpiperazine, Its Metabolite N-Benzylethylenediamine, and Its Disubstituted Analogue N,N'-Dibenzylpiperazine on the Acquisition, Formation, and Consolidation of Memory in Mice" Pharmacology 99(5-6): 268-274, 2017
• M.G. Blake et alia: “Hippocampal α7-Nicotinic Cholinergic Receptors Modulate Memory Reconsolidation: A Potential Strategy for Recovery from Amnesia” Neurobiol. Of Learning and Memory 106: 193-203, 2013
• O.D Can et alia: “Anti-depressant-like Effect of Vitexin in BALB/c Mice and Evidence for the Involvement of Monoaminergic Mechanisms” Eur. J. Pharmacol. 699 (1-3): 250-257, 2013
• J.L. Balderal-Lopez et alia: “Toxic rather than Neuropharmacological Effect of Ternstroemia Sylvatica Fruits and Identification of 28-O-[β-l-6-rhamnopyranosyl]-R1-barrigenol as a new Compound with Toxic Effects in Mice” Pharmaceutical Biology 51 (11), 2013

• J.R. Boissier et P. Simon: "Dissociation de deux composantes dans le comportement d’investigation de la souris" Arch. Int. Pharmacodyn. 147, No. 3-4, 385-393, 1964
• J.R. Boissier et P. Simon: "L’utilisation d’une réaction particulière de la souris (méthode de la planche a trous) pur l’étude des médicaments psychotropes" Thérapie XIX: 571-589, 1964