Rodent Treadmill NG with interchangeable lane assembly for rats or mice

Next generation

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Additional Info

SAME DEVICE TO TEST RATS & MICE	MODES: constant, accelerating, custom ramps
SLOPE: positive (uphill) or negative (downhill), from -25 to +25°, in 5° steps	SPEED: from 3 to 100m/min, in steps of 1m/min amps
SHOCK: from 0 to 2mA (in 0.1mA steps), included	DETECTION: via incorporated electronic circuit automati­cally detects speed & absolute and relative distances
CONTROLS: 4”3 touch-screen to set and monitor the test	X-PAD SOFTWARE: brand new, user-friendly version, to set the experiment and manage the results

General
Commands	4”3 touch-screen (resistive)
Read-out	on the touch-screen
Power Requirement	Universal input 85-264 VAC, 50-60Hz, 40W max.
Sound Level	80 dB ca., at maximum speed
Operating Temperature	10° to 40° C
Operation
Speed	adjustable in the range 3 to 100m/min, in steps of 1m/min
Mode	constant, ramp (accelerating), multi-step ramp (NEW!)
Slope	Manual tilting, positive (uphill) or negative (downhill) from -25° to +25°, in steps of 5°
Shocker	included
Shock	from 0 to 2mA (in 0.1mA steps), 1, 2 or 3Hz
Start/Stop	from the touch-screen
Detection	via incorporated electronic circuit
Results	Speed and distances (absolute and relative)
Data Acquisition	via dedicated X-PADsoftware, provided
Data Portability	by USB flash drive
TTL Output	Shock status (for each lane) and speed
Data	exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
Configurations	exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
Physical

Total Weight	47302 & 47303 : 22Kg – 47300 : 27Kg
Shipping Weight	47302 & 47303 : 35Kg – 47300 : 40Kg approx.
Dimensions	56(w)x67(d)x35(h)cm
Packing Dimensions	47302 & 47303     : wooden crate, 77x65x63cm
	47300         : wooden crate, 82x71x57cm
Warranty	47300 is covered by a 24-month warranty

“Exercise is a multifactorial activity that affects virtually every organ and tissue in the body. Not only does exercise contribute many health benefits, but lack of exercise is im-plicated in many chronic health problems.

As evidence continues to accumulate concerning the impressive range of health benefits that exercise confers, biomedical researchers have increasingly become interested in conducting systematic studies of exercise to further define those benefits”.

Fatigue is a common and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding of fatigue-like behavior in rodents and many other exercise paradigms and study future treatment of fatigue.

Treadmills are rolling belts (tapis-roulants) with presettable speed and adjustable uphill and downhill inclination (slope), enabling forced exercise training and accurate testing of fatigue in lab animals.

“Treadmill running has been used extensively over the past decades to study behavioral, physiological, biochemical, and, more recently, molecular responses to both acute exer-cise stress and chronic exercise training. Although investigators have used a wide variety of species (…) for treadmill running studies, they have used rodents in most of these studies.

Treadmill running has the distinct advantage over other forms of exercise, including spontaneous wheel running and swimming, that the total amount of external work done by the rat can be easily calculated.

Treadmill running may be construed as a form of forced exercise in which the animal does not have a choice of participating in the activity. Because of this, noxious stimuli (e.g., electric shock and bursts of high-pressure air) may be needed to motivate the animals to exercise” 

(from Resource Book for the Design of Animal Exercise Protocols, APS, Feb 2006)

 

47302	Rat Treadmill NG, complete with following accessories
47300-001	Tapis-Roulant with touch-screen controller and shocker
47300-002	3-Lane partition assembly for Rats, each lane 45x11x15(h)cm, with transparent cover
E-AU 041	USB pen drive, including: 47300-302      Instruction Manual   X-PAD Software Package
47303	Mouse Treadmill NG, complete with following accessories
47300-001	Tapis-Roulant with touch-screen controller and shocker
47300-003	6-Lane partition assembly for Mice, each lane 45x5.5x7(h)cm, with transparent cover
E-AU 041	USB pen drive, including: 47300-302      Instruction Manual   X-PAD Software Package
47303	Combo Package: Mouse & Rat Treadmill NG, complete with following accessories
47300-001	Tapis-Roulant with touch-screen controller and shocker
47300-003	6-Lane partition assembly for Mice, each lane 45x5.5x7(h)cm, with transparent cover
E-AU 041	USB pen drive, including: 47300-302      Instruction Manual   X-PAD Software Package
OPTIONAL
47313	Mouse Treadmill NG, complete with standard accessories and in alternative to 47300-003:
47300-013	6-lane assembly (each lane 45x5.5, height 15cm, without lid, for te­thered mice)

 

47302	Rat Treadmill NG: tapis-roulant with touch-screen controller and sho­cker. With 3-lane partition assembly 47300-002 (each lane 45x11x15(h) cm). Including shocker, manual til­ting (-45/+45), transparent cover. Complete with X-PAD software, USB output, USB flash drive
47303	Mouse Treadmill NG: as above, with 3-lane partition assembly 47300-002 (each lane 45x5.5x7(h)cm).
X-PAD	Dedicated Software Package
E-WP 008	Mains Cord

 

Working with both rats and mice? You should consider the Combination Package 47300, including the main unit and both Mouse and Rat in­terchangeable lane-assemblies

 

47300	Combo-Package for Mouse & Rat
47300-013	Mouse 6-lane high-wall partition assembly (each lane 45x5.5, height 15cm, without lid, for tethered mice)

  

Bibliography on 47300

• Exercise Ameliorates Motor Deficits and Improves Dopaminergic Functions in the Rat Hemi-Parkinson's Model YH Chen, TT Kuo, JH Kao, EYK Huang, TH Hsieh… - Scientific Reports, 2018

• American Physiological Society: “Resource Book for the Design of Animal Exercise Protocols” February 2006
• O.J. Kemi et alia: “Intensity-Controlled Treadmill Running in Mice: Cardiacand Skeletal Muscle Hypertrophy” J. Appl. Physiol. 93: 1301-1309, 2002
• X.Q. Wang & G.W. Wang: “Effects of Treadmill Exercise Intensity on Spatial Working Memory and Long-Term Memory in Rats” Life Sciences 149: 96-103, 2016
• M. Shinozaki et alia: “Combined Treatment With Chondroitinase ABC and Treadmillrehabilitation for Chronic Severe Spinal Cord Injury in Adult Rats” Neuroscience Res 113: 37-47, 2016