Pain and Inflammation

37140	Plethysmometer
37215	Analgesy-Meter
35100	Hot/Cold Plate
37370	Plantar Test (Hargreaves Apparatus)
37360	Tail-Flick Unit
37300	I.R. Heat-Flux Radiometer
37450	Dynamic Plantar Aesthesiometer
38500	P.A.M. Pressure Application Measurement
37450/277	Von Frey Hairs (with grid)
31300	Orofacial Stimulation Test (Fehrenbacher, Henry, Hargreaves method)
38450	e-VF Electronic Von Frey

Motory Coordination, Grip Strength, Activity

47200	NEW Grip Strength Meter (mice and rats)
47420	Activity Cage
47700	Rat Rota-Rod
47600	Mouse Rota-Rod
43000	Rotometer
6650	Hole Board
1800/50	Activity Wheels

Ventilators and Gas Anesthesia

28025	Mouse Ventilator
5025	Dog Ventilator
6025	Cat/Rabbit Ventilator
7020	Bronchospasm
21100	Gas Anesthesia System
7900/10	Anesthetizing Box
7025	Rodent Ventilator

Behaviour, Conditioning, Reward

46000	Fear Conditioning System
7530	Automatic Reflex Conditioner (Active Avoidance)
7550	Passive Avoidance - step through
7570	Passive Avoidance - step down
42502/3	Place Preference (CPP)
47500/50	Learned Helplessness
7595	Isolation Cubicle
45100	Lickometer Vogel Test

Behaviour, Mazes, Tracking

46503	Sociability Apparatus (3-chambered social test)
40100	Atlantis Platforms for Water Maze
60000	Any-maze Video-Tracking Software
40125/55/85	Water Maze Pool
40192/3	Barnes Maze
40142/3	Elevated Plus Maze
47432	Mouse Open Field, 44cm
40163	Elevated Zero-Maze
41153	8-Arm Radial Maze for Mouse

Tissue baths, Transducers, Recorders

4000	Isolated Organ Baths
3165	Multiplexing Pulse Booster
7003/4/5/10	Isometric Force Transducers
7006	Isotonic Transducer
14900	Superfusion System
4050	Isolated Organ Baths - 2 chambers
4400	Isolated Organ Baths - 4 chambers
3200	Digital Stimulators
17304	NEW DataCapsule-Evo Digital Recorder

Miscellaneous, ECT, LMD

7950	Small Animal Decapitator
2600	Multi-Function Printer - 6 channels
57800	ECT Unit
53500	Lesion Making Device
51600	Stoelting Stereotaxic Instrument
5000	KDS Infusion Pumps
57145	New Mini Printer

Blood Pressure, Vital Functions

58500	Blood Pressure Recorder, non Invasive
17844	Blood Pressure Transducer, Invasive
2900	Pressure Transducer Calibrator
58000/845	Rat Heater
58000/850	Rat Scanner
58000/840	Mouse Heater
MouseOx	Pulse Oximeter for Mice & Rats

Metabolism, Feeding Behaviour

41800	Metabolic Cages
47552	Rat Feeding & Activity Analyser
47553	Mouse Feeding & Activity Analyser

Muromachi Microwave Fixation

MMW-05

Microwave Brain Fixation NEW 5KW

Neuropathic Pain, Hyperalgesia, Inflammation,

37215	Analgesy-Meter
35100	Hot/Cold Plate
38500	P.A.M. Pressure Application Measurement
37370	Plantar Test (Hargreaves Apparatus)
37140	Plethysmometer
37360	Tail-Flick Unit
31300	Orofacial Stimulation Test (Fehrenbacher, Henry, Hargreaves method)

Allodynia, Hypersensitivity, Somatosensation

37450	Dynamic Plantar Aesthesiometer
37450/277	Von Frey Hairs (with grid)
35100	Hot/Cold Plate
38500	P.A.M. Pressure Application Measurement
38450	e-VF Electronic Von Frey

Motor Function, Parkinson’s, Strength, Exercise

47600	Mouse Rota-Rod
47700	Rat Rota-Rod
43000	Rotometer
47420	Activity Cage
4000	Isolated Organ Baths
47432	Mouse Open Field, 44cm
47200	NEW Grip Strength Meter (mice and rats)

Ventilation, Anesthesia, Surgical Monitoring

58500	Blood Pressure Recorder, non Invasive
17844	Blood Pressure Transducer, Invasive
6025	Cat/Rabbit Ventilator
5025	Dog Ventilator
21100	Gas Anesthesia System
28025	Mouse Ventilator
MouseOx	Pulse Oximeter for Mice & Rats

Memory, Learning, Alzheimer

7530	Automatic Reflex Conditioner (Active Avoidance)
46000	Fear Conditioning System
40100	Atlantis Platforms for Water Maze
7570	Passive Avoidance - step down
7550	Passive Avoidance - step through
60000	Any-maze Video-Tracking Software
40125/55/85	Water Maze Pool
40192/3	Barnes Maze
47432	Mouse Open Field, 44cm
41153	8-Arm Radial Maze for Mouse

Addiction and Reward, Social Behaviour and Autism

46503	Sociability Apparatus (3-chambered social test)
42502/3	Place Preference (CPP)
5000	KDS Infusion Pumps
60000	Any-maze Video-Tracking Software
45100	Lickometer Vogel Test
47432	Mouse Open Field, 44cm

Anxiety, Depression, Fear, Stress

47500/50	Learned Helplessness
47420	Activity Cage
60000	Any-maze Video-Tracking Software
45100	Lickometer Vogel Test
40125/55/85	Water Maze Pool
40192/3	Barnes Maze
40142/3	Elevated Plus Maze
47432	Mouse Open Field, 44cm
40163	Elevated Zero-Maze

Electrolytic Lesions and Infusion

53500	Lesion Making Device
51600	Stoelting Stereotaxic Instrument
5000	KDS Infusion Pumps
17304	NEW DataCapsule-Evo Digital Recorder

Epilepsy, Seizures, Convulsions (ECT)

43000	Rotometer
57800	ECT Unit

Brain Chemistry, Phosphorylation,

MMW-05

Microwave Brain Fixation NEW 5KW

Products > Motory Coordination, Grip Strength, Activity > 6650 - Hole Board

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6650 - Hole Board

The Hole-Board 6650 has been conceived to study the behavior of the mouse confronted with a new environment (head plunging stereotype) according to the method devised by Boissier-Simon.

The Hole-Board 6650 has been conceived to study the behavior of the mouse confronted with a new environment (head plunging stereotype) according to the method devised by Boissier-Simon. The test enables the initial exploratory activity of the animal and its variations brought about by psychotropic drugs to be unmistakably assessed. The recording takes place automatically, via miniature I.R. emitters/receivers embodied in the "holes" of the board

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Features and Benefits
Specifications
Accessories
Bibliography

FEATURE	BENEFIT
Simple and classical test	Reliable, requires very little training
16 holes, each containing 1 pair of IR photocells	Head Plungings are accurately counted
Can be connected to Multifunction Printer	Up to 6 hole boards can be run simultaneously

Starting	via RESET switch located on the front panel
Activity counter	4-digit LED display
Self-diagnosis	by test-key and 2-LED configuration
Connection to PC	through DELTA 15-pin connector, via multifunction Printer/ WinDAS Software
Power Requirement	115 or 230 V, 50/60 Hz, 15 W max
Operating Temperature	0° to 30° C
Sound Level	negligible

Physical Dimensions
Dimensions (board):	cm 40 (w) x 40 (d) x 7-18 (h)
Dimensions (control unit):	cm 15 (w) x 26 (d) x 25 (h)
Weight:	5.50 Kg
Shipping Weight:	10.50 Kg approx
Packing Dimensions:	67 x 42 x 53 cm

3157 Timer: an optional accessory, which enables the researcher to preset “timed operation” to all instruments in which this feature is not provided.

Method Paper

- J.R. Boissier et P. Simon: "Dissociation de deux composantes dans le comportement d’investigation de la souris " Arch Int. Pharmacodyn 147, No. 3-4, 1964.

- J.R. Boissier et P. Simon: "L’utilisation d’une réaction particulière de la souris (Méthode de la planche à trous) pour l’étude des médicaments psychotropes " Thérapie XIX, 571-589, 1964.

Papers Mentioning 6650

- N. Meiri et alia: "Reversible Antisense Inhibition of Shaker-like Kv1.1 Potassium Channel Expression Impairs Associative Memory in Mouse and Rat" Proc. Natl. Acad. Sci. USA, 94, 4430-4434, 1997.

- L. Jasmin et alia: "The NK1 Receptor Mediates Both the Hyperalgesia and the Resistance to Morphine in Mice Lacking Noradrenaline" Proc. Natl. Acad. Sci. USA., 99(2),1029–1034, 2002.

- A. L. da Silva & E. Elisabetsky: “Interference of Propylene Glycol with the Hole-Board Test” Brazilian J. Med. Biol. Res., 34(4), 545-547, 2001.

- H. Shaheen et alia: “Effect of Psidium Guajava Leaves on Some Aspects of the Central Nervous System in Mice” Phytotherap. Res., 14(2), 107-111, 2001