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37450 - Dynamic Plantar Aesthesiometer
The Dynamic Plantar Aesthesiometer has been designed to automate the assessment of “touch sensitivity” on the plantar surface of rats or mice and comes ready to work with both Mice and Rats. It is known by some as the Electronic Von Frey or Plantar Von Frey instrument, but differently from Von Frey devices, Latency time, and Actual Force at the time of paw withdrawal reflex are recorded.
The Dynamic Plantar Aesthesiometer has been designed to automate the assessment of “touch sensitivity” on the plantar surface of rats or mice and comes ready to work with both Mice and Rats. It is known by some as the Electronic Von Frey or Plantar Von Frey instrument, but differently from Von Frey devices, Latency time, and Actual Force at the time of paw withdrawal reflex are recorded.
A moveable force actuator is positioned below the plantar surface of the paw and the desired force and force speed (ramp) is applied.
A Von Frey – type 0.5 mm filament exerts increasing force, until the animal twitches its paw.
The new model encompasses:
- a movable touch-stimulator unit, well proven in previous model, complete with filament actuator and adjustable angled-mirror
- a microprocessor controlled electronic unit, of new design provided with graphic display, internal memory for data storage, memory stick and optional printer
- a large testing surface
- a new modular animal enclosure, offering from 3 to 12 spaces
Data may be easily ported to a memory stick or directly to computer.
Perforated Metal Platform and multi-configuration animal enclosure, from 3 - 12 chambers, are included.
Features and Benefits
Specifications
Accessories
Bibliography
| FEATURE |
BENEFIT |
| The force is automatically applied |
Consistency in force application, rate and direction |
| The user only has to press a button |
The test is quicker and less tedious than VF hairs |
| Force threshold and ramp can be preset |
More parameters to fit with virtually any experimental need |
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| Starting: |
via keys on the touch-stimulator vessel |
| Force range: |
0 to 50.0 grams, in 0.5 g steps |
| Force increasing rate: |
adjustable in the interval 1 to 20 seconds, in 1 s steps |
| Filament travel: |
12 mm |
| Latency time: |
read-out on graphic display, in 0.1s steps |
| Connection to PC: |
through DELTA 9-pin connector |
| Universal Mains: |
85-264 VAC - 50-60Hz - 20 W max |
| Total Weight: |
Kg. 10.20 |
| Shipping Weight |
Kg. 18.50 approx |
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- D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”. Nature NSC, 2010
- L. Ramer et alia: "Rho-Kinase Inhibition Enhances Axonal plasticity and Attenuates Cold Hyperalgesia after Dorsal Rhizotomy" J. Neuroscience, 24 (48), 10796-10805, 2004
- E. Escribano et alia: "Rapid Human Skin Permeation and Topical Anaesthetic Activity of a New Amethocaine Microemulsion" Skin Pharmacol. Physiol., 18, 294-300, 2004
- G. Villetti et alia: "Antinociceptive Activity of the N-Methyl-D-aspartate Receptor Antagonist N-(2-Indanyl)-glycinamide Hydrochloride (CHF3381) in Experimental Models of Inflammatory and Neuropathic Pain" J. Pharmacol. Exper. Therap., 306, 804-814, 2003
- M. Isabel Arévalo et alia: "Thermal Hyperalgesia and Light Touch Allodynia After Intradermal Mycobacterium butyricum Administration in Rat" Inflammation, 27 (5), 293-299, 2003
