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31300 - Orofacial Stimulation Test (Fehrenbacher, Henry, Hargreaves method)

The Orofacial Stimulation Test by Ugo Basile measures hypersensitivity to thermal or mechanical stimulation of the trigeminal area. Rats voluntarily contact a thermal or a mechanical stimulator with their vibrissal pad (unshaved) in order to access a food reward.

Metrics obtained are the duration of feeding and the number of feeding attempts, measured by interruption of an infrared barrier traversing the opening to the reward. Feeding duration and number of attempts are strongly dependent on changes in the applied thermal or mechanical stimulus.

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- Mechanical and Thermal nociception assays within the same experiment


- Integrates higher-order brain functions into measurements of orofacial nociception


- Intact vibrissal pad, as the test does not require any vibrissal shaving


- High throughput: up to 16 animals can be tested simultaneously


Ugo Basile Srl - Via Giuseppe Di Vittorio 2 - 21036 GEMONIO – Varese – ITALY - tel +39 0332 744574 fax +39 0332 745488 - P.IVA 02728350121 -