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Electrolytic Lesions and Infusion

53500	Lesion Making Device
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Products > Electrolytic Lesions and Infusion > 53500 - Lesion Making Device

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53500 - Lesion Making Device

The Ugo Basile Lesion Maker has been designed for the production of localized electrolytic lesions in small animals where DC is preferred to RF, to produce the lesion.

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Features and Benefits
Specifications
Bibliography

FEATURE	BENEFIT
Current generator protected against short circuit	Prevents damage to electronics. Safety
Wide current output range (10uA-99mA) and duration (1-99 s)	Allows for virtually any procedure
Violation LED indicator	Indicates if compliance is violated

Lesion Making Device:	DC constant Current	Operating Temperature:	0° to 30° C
Current Range:	from 10 µA to 99 mA or manually controlled	Sound Level:	<45 dB
Max. Electrode Resistance:	20 MOhm (10µA) down to 2 KOhm (100mA)	Violation Monitoring:	via yellow LED
Power Monitoring:	via red LED	Power Requirement	115 or 230 V, 50/60 Hz, 20 W max

Physical Dimensions:
Dimensions	25(w) x 15(d) x 11(h) cm
Weight	Kg 1,5
Shupping Weight	Kg 2,8 approx
Packing Dimensions	46 x 29 x 24 cm

PAPERS MENTIONING UGO BASILE LESION MAKER

- M.B. Gomes et alia: "Glucose levels Observed in Daily Clinical Practice induce Endothelial Dysfunction in the Rabbit Macro- and Microcirculation" Fund. & Clin. Pharmacol. 18 (3), 2004

- T. Lee and J.J. Kim: "Differential Effects of Cerebellar, Amygdalar, and Hippocampal Lesions on Classical Eyeblink Conditioning in Rats" J. Neuroscience 24 (13): 3242-3250, 2004

- K.C. Bicego and L.G.S. branco: "Discrete Electrolytic lesion of the Preoptic Area Prevents LPS-Induced Behavioral Fever in Toads" J. Exper. Biol. 205: 3513-3518, 2002

- J.S. Lonstein et alia: "Role of the Midbrain Periaqueductal Gray in Maternal Nurturance and Aggression: c-fos and Electrolytic Lesion Studies in Lactating Rats" J. Neuroscience. 17 (9): 3364-3378, 1997

- P. Ruggeri et alia: "Role of Ventrolateral Medulla in Reflex Cardiovascular Responses to Activation of Skin and Muscle Nerves" Am. J. Physiol. 268: 1464-1471, 1995

PAPERS MENTIONING LESION MAKING TECHNIQUE

- J.A. Harvey et alia: “The Effect Of Unilateral And Bilateral Medial Forebrain Bundle Lesions On Brain Serotonin“ J. Pharmac. Exper. Therap. 140: 103-110, 1963

- R.Y. Moore & A. Heller: “Monoamine Levels and Neuronal Degeneration in Rat Brain Following Lateral Hypotalamic Lesions“ J. Pharmac. Exper. Therap. 156: 12-22, 1967

- M. Cole: “Retrograde Degeneration Of Axon And Soma In The Nervous System“ in: The Structure and Function of Nervous Tissue, Vol. I, edited by G.H. Bourne, New York: Academic Press, 1968

- J.J. Bernstein & M.E. Bernstein: "Axonal Regeneration And Formation Of Synapses Proximal To The Site Of Lesion Following Hemisection Of The Rat Spinal Cord” Expl. Neurol. 30: 336-351, 1971

- G. Lynch et alia: “Postlesion Axonal Growth Produces Permanent Functional Connections” Science: 180: 1364-1366, 1973

- S. Finger et alia: “Brain Damage and Behavioural Recovery: Serial Lesion Phenomena” Brain Res. 63: 1-18, 1973

- S.D. Glick: “Changes in Drug Sensitivity and Mechanisms of Functional Recovery Following Brain Damage“ in: Plasticity and Recovery of Function in the Central Nervous System, edited by D.G. Stein, J.J. Rosen & N. Butters, New York: Academic Press, 1974

- J.F. Marshal et alia: “Nigrostriatal Bundle Damage And The Lateral Hypothalamic Syndrome“ J. Comp. Physiol. Psychol. 87: 808-830, 1974

- B.S. Rosner: “Recovery of Function and localization of function in historical perspective“ in: Plasticity and Recovery of Function In The Central Nervous System, edited by D.G. Stein, J.J. Rosen & N. Butters, New York: Academy Press, 1974

- P. Van Sommers & P. Teitelbaum: “Spread Of Damage Produced By Electrolytic Lesions In The Hypothalamus“ J. Comp. Physiol. Psychol. 86: 288-299, 1974

- C.A. Boast et alia: “A Caution To Brain Scientists: Unsuspected Hemorrhagic Vascular Damage Resulting From Mere Electrode Implantation” Brain Res. 103: 527-534, 1976

- G. Lynch: “Some Difficulties Associated With The Use Of Lesion Techniques In The Study Of Memory“ In: Neural Mechanisms of Learning and Memory, edited by M.R. Rosenzwei

g & E.L. Bennett, Cambridge: MIT Press, 1976

- T. Ljundberg & U. Ungerstedt: “Reinstatement of Eating by Dopamine Agonists in Aphagic Dopamine Denervated Rats“ Physiol. Behav. 16: 277-283, 1976

- N.Å. Svendgård et alia: “Regeneration Of Central Cholinergic Neurones In The Adult Rat Brain“ Brain Res. 102: 1-22, 1976

- J. R. West et alia: “An Experimental Test of Diachisis“ Behav. Biol. 18: 419-425, 1976.