38500 - P.A.M. Pressure Application Measurement
The P.A.M. (Pressure Application Measurement) device is a novel tool for measuring mechanical pain threshold. It was specifically designed for Arthritis research and is therefore especially suited to assess joint hypersensitivity in rodents knees or ankles. The PAM device can also be used to measure mechanical sensitivity in mice and rats paw, by using a specific Paw Pressure Transducer (optional).
The P.A.M. (Pressure Application Measurement) device is a novel tool for measuring mechanical pain threshold. It was specifically designed for Arthritis research and is therefore especially suited to assess joint hypersensitivity in rodents knees or ankles. The PAM device can also be used to measure mechanical sensitivity in mice and rats paw, by using a specific Paw Pressure Transducer (optional).
The PAM device has been designed and validated specifically for the mechanical stimulation and assessment of joint pain, as it applies a quantifiable force for direct stimulation of the joint and for automatic readout of the response.
The operator simply wears a special force sensor on his or her thumb and the peak amplifier measures the force which elicits the animal response (normally, limb withdrawal).
Each PAM device comes standard with two force sensors, which have been specially designed to apply force to rat and mouse joints.
Features and Benefits
Specifications
Accessories
Bibliography
Pictures
| FEATURE |
BENEFIT |
| The force is applied directly to the joint |
Direct measurent of evoked pain |
| Specifically designed for arthritis research |
The applicators are shaped for rodents knee and ankle |
| Paw pressure transducer is an optional |
PAM can also be used as a hand-held Randall-Selitto device |
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| Resolution: |
0.1 g |
| Maximum applicable Forse: |
1500gf |
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| 38500-006: |
Paw Transducer |
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ACKNOWLEDGEMENTS:
The PAM device was invented and validated in the University of Edinburgh by the team of Prof. Daniel McQueen, Susan Bond and colleagues and Dr. Harry Brash, who built the first prototypes.
BIBLIOGRAPHY:
- N. J. Barton et al. 2007. Pressure application measurement (PAM): A novel behavioural technique for measuring hypersensitivity in a rat model of joint pain. Journal of Neuroscience Methods 163, 67–75.
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38500 Pam
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ThumbTransducer
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PAM Complete Kit
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